PHARMACOLOGY QUIZZES 55 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a Meglitinide drug?
A. Hydrochlorothiazide  
B. Nateglinide 
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: B. Nateglinide 

02. Which of the following drug belongs to Sulfonylureas?
A. Niacin
B. Cefoxitin 
C. Tolbutamide 
D. Urae
E. Oxacillin

Answer: C. Tolbutamide 

03. Which one of the following drugs is first generation flouroquinolone?
A. Ciprofloxacin
B. Levofloxacin 
C. Nalidixic acid
D. Moxifloxacin


Answer: C. Nalidixic acid

04. A drug that belongs to thiazolidinediones  is one of the following?
A. Pioglitazone 
B. Ethacrynic Acid
C. Cefazolin 
D. Sulbactam
E. A & B

Answer: A. Pioglitazone 

05. Which one of the following drugs is 2nd generation flouroquinolone?
A. Ciprofloxacin
B. Levofloxacin 
C. Nalidixic acid
D. Moxifloxacin

Answer: A. Ciprofloxacin

06. A disease in which blood vessels become inflamed and this inflammation leads to restriction of blood flow to organs and tissues also sometimes permanently damage organs is called?
A. Steven-johnson syndrome
B. Ductus arteriosus
C. Churg Strauss syndrome
D. Reye syndrome
E. Hypotrichosis

Answer: C. Churg Strauss syndrome 

07. Which of the following drug can disrupt the enteric coating by increasing the Gastric PH?
A. Sitagliptin 
B. Cefoxitin 
C. Glimepiride  
D. Omeprazole 
E. Oxacillin

Answer: D. Omeprazole 
Because when Omeprazole increase the gastric PH towards neutral. when PH of gastric acid increased this results in providing  the enteric coated tablets a favourable environment to release drug.


08. Which one of the following is the adverse effect of ACE inhibitors?
A. Dry cough
B. Skin rashes
C. hypokalaemia
D. A & B
E. All of the above


Answer: D. A & B

09. A drugs interfere with metabolism of azathioprine requiring a reduction in dosage?
A. Probenecid
B. Sulfinpyrazone
C. Colchicine
D. Allopurinol


Answer: D. Allopurinol

10. Aldosterone production is reduced by using one of the following drugs?
A. Lisinopril
B. Aspirin
C. Erythromycin
D. Diltiazem


Answer: A. Lisinopril

11. Following disease is inherited disorder of copper metabolism characterized by reduced serum copper & increased cincentration of copper in brain & viscera
A. parkinsons disorder
B. wilsons disorder
C. restless legs syndrome
D. Gout

Answer: B. wilsons disorder

12. Surgical removal of Fallopian tubes is called?
A. Salpingdectomy
B. Ostectomy
C. Posthectomy
D. Rhinectomy
E. Orchiectomy

Answer: A. Salpingdectomy

13. Which one of the following drugs is an inhibitor of folate synthesis?
A. Sulfasalazine
B. Erythromycin
C. Clarithromycin
D. Levofloxacin


Answer: A. Sulfasalazine

14. Which of the following drugs bind to the 50S subunit causing inhibition of translocation?
A. Erythromycin
B. Clindamycin
C. Streptomycin
D. A & B
E. All of the above


Answer: D. A & B

15. Salicylates Potentiate the effects of following drugs as a drug interaction?
A. Anticoagulants
B. Thrombolytic agents
C. PPIs
D. A & B
E. All of the above 

Answer: D. A & B

16. Which one of the following neurotransmitters mediates the Na+ influx into the postsynaptic neuron and works as excitatory?
A. Substance P
B. Met-enkephalins
C. Glutamate
D. GABA
E. Serotonin

Answer: C. Glutamate

17. Which one of the following symptoms is linked with the overdose of the Ganglion blocker drug?
A. Increased blood pressure
B. Miosis
C. Tachycardia
D. Increased Sweating
E. Increased bowel movement

Answer: C. Tachycardia
Because the pupil and the sinoatrial node are dominated by the Parasympathetic system when the sympathetic and Parasympathetic systems are blocked by ganglion blocker drugs. leading to tachycardia and Mydriasis.
 

18. A 40-year-old female is on 6-mercaptopurine for treatment of acute lymphocytic leukemia. Which of the following drugs may not be used to reduce the resultant uric acid levels?
A. Allopurinol
B. Colchicine
C. Indomethacin
D. Probenecid
E. Sulindac


Answer: A. Allopurinol 

19. Which one of the following types of hepatitis is not a chronic disease and commonly encountered infection?
A. Hepatitis A
B. Hepatitis B
C. Hepatitis C
D. A & B
E. B & C

Answer: A. Hepatitis A

20. When the level of prostacyclin is decreased then the binding of prostacyclin to platelet receptor is also decreased resulting in?
A. Increase level of intracellular cAMP
B. Lower level of intracellular cAMP
C. Increase level of Ca++
D. Decrease level of Ca++
E. Both B & C

Answer: E. Both B & C

21. Sympathetic nervous system has a following type of response?

A. Diffuse

B. Discrete 

C. Minimal 

D. Extensive 

Answer: A. Diffuse

22. ParaSympathetic nervous system has a following type of response?

A. Diffuse

B. Discrete 

C. Minimal 

D. Extensive 

Answer: B. Discrete 

23. Following drugs is cleared by organ independent metabolism (Hofmann elimination)?

A. Cisatracurium

B. Pancuronium

C. Vecuronium

D. Rocuronium

Answer: Cisatracuronium

Pancuronium is renally eliminated and can't be used in renal failure patients.

Vecuronium and rocuronium  are hepatically metabolized and can't be used in liver disease patients.

24. Systemic lupus erythematosus (caused by antibodies to DNA, histone, and antigens of the nucleus)  is an example of?

A. Type I hypersensitivity 

B. Type II hypersensitivity 

C. Type III hypersensitivity 

D. Type IV hypersensitivity 

Answer: Type III hypersensitivity 

Examplea: Hypersensitivity reactions involves antibody dependent reactions to soluble antigens by forming immune complex between antibody and soluble antigen, 

Arthus Reactions ( subcutaneous immune complex formation occurring at a local site in and around the wall of small blood vessels

25. Tuberculina reaction (local reaction of inflammation and redness at the site of subcutaneous injection of prepared antigen 

From Mycobacterium tuberculosis  Is following type?

A. Type I hypersensitivity 

B. Type II hypersensitivity 

C. Type III hypersensitivity 

D. Type IV hypersensitivity 

Answer: D. Type IV hypersensitivity also called delayed type hypersensitivity DTH Type of hypersensitivity mediated by a memory T-cell response that have been sensitised to an allergin by a previous contact recruit other leukocytes to the site of allergin upon a later encounter

Because of the recruitment a delay occurs in the allergic reaction.

Example: 

Contact dermatitis allergen contact with the epidermis resulting in inflammation and redness caused by infiltration of leukocytes and cytokine release

Granulomatous reaction Stimulation from a foreign body or particulate such as talc or silica resulting in a granuloma, which is a mass of lymphocytes and macrophages surrounding an allergen too large to be phagocytized.