PHARMACOLOGY QUIZZES 39 | Multiple Choice Questions| Medical Exam Preparations

01. Beta-Blocker drug is following?
A. Atropine
B. Esmolol
C. Acetylcholine
D. Succinylcholine
E. Tamsulosin

Answer: B. Esmolol


02. Which one of the following drugs is an adrenergic antagonist Alpha Blocker drug?
A. Phenoxybenzamine
B. Metoprolol
C. Mecamylamine
D. Atracurium
E. Tacrine

Answer: A. Phenoxybenzamine

03. Which of the following drug belongs to lincosamide antibiotics?
A. Clindamycin
B. Linezolid
C. Ciprofloxacin
D. Oxytetracycline
E. Sulbactam

Answer: A. Clindamycin

04. Which one of the following drugs is a Proteas inhibitor?
A. Abacavir
B. Delavirdine
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin 

Answer: C. Atazanavir

05. Which one of the following drugs is a Proteas inhibitor?
A. Abacavir
B. Delavirdine
C. Darunavir
D. Maraviroc
E. Indanyl carbenicillin 

Answer: C. Darunavir

06. Which of the following drug belongs to the Nonnucleoside reverse transcriptase inhibitor?
A. Abacavir
B. Efavirenz
C. Atazanavir
D. Maraviroc
E. Indanyl carbenicillin

Answer:  B. Efavirenz

07. Immune-related problem is one of the following?
A. High Blood pressure 
B. Fever 
C. Aids
D. Headache 

Answer: C. Aids 

08. Peripheral resistance is linked with one of the following issues?
A. Blood pressure 
B. Fever 
C. Aids
D. Headache 

Answer: A. Blood pressure

09. Ethacrynic acid belongs to one of the following classes of diuretics?
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium-sparing diuretics
D. Carbonic anhydrase inhibitors

Answer: B. Loop Diuretics

11. Which of the following drugs causes Rhabdomyolysis as an adverse effect?
A. Digoxin
B. Dronedarone
C. Simvastatin
D. Warfarin
E. Amikacin

Answer: C. Simvastatin

12. Which one of the following drugs is effective only for the influenza A virus?
A. Zanamivir 
B. Rimantadine 
C. Oseltamivir
D. A & B
E. None of these 

Answer: B. Rimantadine 

13. 𝛃 receptors have a high sensitivity for which of the following drug?
A. Epinephrine 
B. Norepinephrine 
C. Isoproterenol
D. A & B
E. All of these 

Answer: C. Isoproterenol


14. A cytokine that induces proliferation of antigen-primed T cells along with enhancing the activity of NK cells?
A.  Interleukin-1 (IL-1)
B.  Interleukin-2 (IL-2)
C. Interferon-gamma 
D. Tissue necrosis factor-alpha 


Answer: B. Interleukin-2


15. The binding of a drug to plasma proteins will tend to: 
A. Decrease half-life. 
B. Decrease its rate of glomerular filtration. 
C. Increase its rate of biotransformation. 
D. Increase its concentration in the plasma. 
E. Increase its pharmacological activity


Answer: B. Decrease its rate of glomerular filtration

16. A disease that is characterized by the movement of gastric contents from the stomach into the esophagus?
A. Peptic Ulcer disease
B. GERD 
C. Dyspepsia
D. A & B  

Answer: B. GERD

17. Which one of the following drugs has a beta effect (vasodilation) at low doses but when the dose is increased it causes vasoconstriction (Alpha effect) at high doses?
A. Clonidine
B. Metaproterenol
C. Epinephrine
D. Isoproterenol
E. Methoxamine

Answer: C. Epinephrine

18. Which of the following drugs has the longest duration of bronchodilation?
A. Epinephrine
B. Isoproterenol
C. Albuterol
D. Salmeterol
E. Metaproterenol

Answer: D. Salmeterol

19. One of the OATPs (Organic anion transporting polypeptides) drugs transporters  OATP4C1 has a mainly limited distribution to the following?
A. Liver 
B. Kidney 
C. Skin 
D. Heart 
E. Stomach 

Answer: B. Kidney 

20. A patient comes with constipation, incontinence, and a fall in blood pressure. He is being treated for cardiac arrhythmias. Which drug is most likely related to these complaints?
a. Propranolol
b. Verapamil
c. Quinidine
d. Amiodarone


Answer: c. Quinidine
c. Quinidine is the right answer, these are due to extra pharmacology attached with quinidine that is alpha blockade and muscarinic blockade.

10. Purple toe syndrome is caused by using the therapy of which drug?
A. Digoxin
B. Phenytoin
C. Cyclosporine
D. Warfarin
E. Amikacin

Answer: D. Warfarin

While treating venous thromboembolism 

Unfractionated Heparin anticoagulant effect is monitored either by 

A. Partial thromboplastin time (aPPT)

B. Anti-Xa levels 

C. Institution specific goal ranges 

While Warfarin anticoagulant effect is monitored via

A. International Normalized ratio (INR)

21. A type of hypersensitivity which is a reaction to tissue or membrane antigens(not soluble). Reaction occur when antibodies to surface antigen bind and causes destruction of cell or tissue?

A. Type I 

B. Type II

C. Type III

D. Type IV

Answer: Type II hypersensitivity 

In type II hypersensitivity antigen is not soluble while in Type III antigen is soluble. 

21. Allergic rhinitis or hay fever, food allergies, eczema, asthma and anaphylaxis are following type of hypersensitivity?

A. A. Type I 

B. Type II

C. Type III

D. Type IV

Answer: Type I hypersensitivity (mediated by elevated IgE production. IgE bound to on the surface of mast cells and release histamine)

Treatment: forms of atopy are treated by hyposensitization which is repeated injection of controlled doses of allergin or by avoiding allergin.

Asthma treated by inhaled bronchodilators and corticosteroids to ease inflammation on passage 

Anaphylactic reactions: Epinephrine as a bronchodilator in emergency, diphenhydramine effective antihistamine and steroid dexamethasone anti inflammatory.

22. Transfusion related reactions caused by incompatible blood type(either the blood typing antigen A, B, or O or the Rh+ or Rh- rhesus antigen) is example of?

A. Type I hypersensitivity 

B. Type II hypersensitivity 

C. Type III hypersensitivity 

D. Type IV hypersensitivity 

Answer: Type II hypersensitivity reactions also called cytotoxic or antibody dependent hypersensitivity.

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PHARMACOLOGY QUIZZES 38 | Multiple Choice Questions| Medical Exam Preparations

01. NucleoSide Reverse Transcriptase inhibitors(NRTIs) drug in Antiviral class?
A. Zidovudine
B. Nevirapine
C. Saquinavir
D. Amprenavir
E. Acyclovir

Answer: A. Zidovudine

02. Which of the following drug is Non-NucleoSide Reverse Transcriptase inhibitors(NNRTIs)?
A. Zidovudine
B. Nevirapine
C. Saquinavir
D. Amprenavir
E. Acyclovir

Answer: B. Nevirapine

03. Which one of the following drugs is a loop Diuretics drug?
A. Chlorthalidone
B. Bumetanide
C. Amiloride
D. Acetazolamide

Answer: B. Bumetanide

04. Following is the 2nd generation cephalosporin drug? 
A. Cefdinir
B. Cefaclor
C. Cefadroxil
D. Cefepime
E. Cephalexin

Answer: B. Cefaclor

05. Miconazole belongs to the following type of drugs class?
A. Antiviral 
B. Antipyretic 
C. Antifungal 
D. Antibiotics 
E. Anti malaria 

Answer: C. Antifungal

06. Amphotericin B belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Antifungal  

Answer: E. Antifungal

07. Abacavir belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: A. Antiviral   

08. Which one of the following drugs belongs to ANTIMETABOLITES drugs for Cancer?
A. 6-thioguanine 
B. Capreomycin
C. Lamivudine 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: A. 6-thioguanine 

09. Which of the following drugs is neuraminidase inhibitor drug?
A. Ibandronate
B.  Zanamivir 
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Zanamivir

10. Which one of the following drugs belongs to inhibitors of viral coating?
A. Acyclovir 
B. Oseltamivir
C. Amantadine
D. Zidovudine 
E. Nevirapine

Answer: C. Amantadine

Limited to influenza A infections.

11. A drug that inhibits replication of the influenza A virus by interfering with viral attachment and uncoating?
A. Acyclovir 
B. Oseltamivir
C. Rimantadine 
D. Zidovudine 
E. Nevirapine

Answer: C. Rimantadine 

12. Which one of the following statements about dobutamine is incorrect?
A. Positive inotropic effect   
B. 𝛃1 receptor stimulator 
C. Treat acute heart failure 
D. Decrease myocardial cAMP 
E. Increase contractility 

Answer: D. Decrease myocardial cAMP

13. Which of the following drugs has/have beneficial role in Torsades de pointes ?
a) Amiodarone
b) Magnesium Sulfate
c) Propranolol
d) Eplerinone
f) b & c


Answer: f) b & c
The correct answer is -- B & C .
Mag Sulf, as we all know, is the DOC for Torsades de pointes .
Propranolol is an adjunct drug useful in it.
And some also chose Amiodarone (option A) - Infact Amiodarone is contraindicated in this condition.

14. A drug that elevate bronchial smooth muscle cAMP leading to decreased intracellular calcium and prompt bronchodilation.
A. Epinephrine 
B. Clonidine 
C. Phenylephrine
D. Albuterol 
E. Dipivefrin 

Answer: D. Albuterol  
Albuterol is a selective beta2 adrenergic agonist.

15. A cytokine that enhances the activity of NK cells and attracts neutrophils and macrophages?
A. Interleukin-1
B. Interleukin-2
C. Interferon gamma
D. Tissue necrosis factor-alpha


Answer: Interleukin-1


16. Amphotericin B exerts its anti-fungal effect by which of the following mechanisms?  
a) Inhibition of cell wall synthesis
b) Inhibition of fungal protein synthesis
c) Inhibition of DNA synthesis
d) Alteration of cell membrane permeability
e) Inhibition of fungal cell wall synthesis



Answer: d) Alteration of cell membrane permeability

17. A disease characterized as recurrent and persistent abdominal discomfort and abdominal pain?
A. Peptic Ulcer disease
B. GERD 
C. Dyspepsia
D. A & B  

Answer: C. Dyspepsia

18. Red man syndrome is caused by 
A. vancomycin
B. penicilin
C. lincosamine
D. cephalosporin 

Answer: A. Vancomycin

19. Which one of the following drugs is a selective Beta-2 adrenergic long-acting bronchodilator?
A. Albuterol
B. Pirbuterol
C. Terbutaline
D. Formoterol
E. Metaproterenol

Answer: D. Formoterol

20. Which one of the following drugs decreases Glucose absorption?
A. Miglitol
B. Metformin
C. Rasagiline
D. Glipizide


Answer: A. Miglitol

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PHARMACOLOGY QUIZZES 37 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a Penicillin drug?
A. Niacin
B. Atorvastatin
C. Fenofibrate
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: E. Indanyl carbenicillin

02. Lisinopril is used to treat one of the following disease?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria  

Answer: B. Blood pressure

03. Which of the following drug belongs to Cephalosporin?
A. Niacin
B. Cefoxitin 
C. Ampicillin 
D. Ezetimibe
E. Oxacillin

Answer: B. Cefoxitin 


04. A drug that belongs to MONOBACTAMS is one of the following?
A. Doripenem
B. Imipenem
C. Cefazolin 
D. Sulbactam
E. A & B

Answer: E. A & B

05. Lopinavir is used to treat one of the following disease?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria  

Answer: A. Viral infection

06. Ritonavir  belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: A. Antiviral  

07. Caspofungin  belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antifungal  
E. Anti malaria 

Answer: D. Antifungal

08. Cefepime belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: D. Antibiotics

09. Rabeprazole is used to treat one of the following disease?
A. Viral infection 
B. Blood pressure  
C. Diabetes 
D. Stomach Ulcer  
E. Malaria  

Answer: D. Stomach Ulcers

11. Carvedilol blocks following receptors?
A. Alpha-1
B. Beta-1
C. Beta-2
D. A & B
C. All of the above


Answer: C. All of the above

12. Does a drug needs continuous infusion due to half-life of minutes to maintain its hypotensive action?
A. Labetalol
B. Nicardipine
C. Sodium nitroprusside
D. Fenoldopam


Answer: C. Sodium Nitroprusside


13. Blood flow to which of the following organs is primarily regulated by the sympathetic nervous system rather than local metabolites?
a) Brain
b) Heart 
c) Skeletal Muscles during exercise
d) Skin


Answer: d) Skin
The answer is d, the circulation to the skin is primarily controlled by the sympathetic nervous system (through alpha1 receptors); circulation to coronary and cerebral is primarily regulated by local metabolic factors, and circulation to skeletal muscles during exercise is regulated primarily by local metabolic factors although at rest controlled by sympathetic nervous system.

14. A cytokine that has a cytotoxic effect on tumor cells and induces cytokine secretion in inflammatory response?
A. Interleukin-1
B. Interleukin-2
C. Interferon gamma
D. Tissue necrosis factor-alpha



Answer: S. Tissue necrosis factor-alpha


15. Which of the following changes will cause an increase in myocardial O2 consumption?
a) Decreased aortic pressure
b) Decreased contractility
c) Decreased heart rate
d) Increased size of the heart


Answer: d) Increased size of the Heart
The answer is d, myocardial O2 consumption is determined by the amount of work done by the heart (amount of tension developed); it is increased by increase in afterload, increased heart rate or stroke volume, or when size of the heart is increased.

16. A disease characterized by lesions of the mucosa of the GIT especially stomach and duodenum regions exposed to gastric juices?
A. Peptic Ulcer disease
B. GERD 
C. Dyspepsia
D. A & B 

Answer: A. Peptic Ulcer disease

17. Acetylation of Isoniazid is inhibited by following drug?
A. Ethionamide 
B. Dapsone
C. Clofazimine
D. Streptomycin


Answer: A. Ethionamide

18. Which one of the following statements about the Aspirin is not right?

A. Decrease alveolar ventilation 
B. Inhibit COX
C. Hydrolysed to Salicylates 
D.  Low dose has 3 hour half life 
E. Prevent sensitisation of pain 

Answer: A. Decrease alveolar ventilation 
Infact it increases alveolar ventilation at therapeutic doses.

19. Which one of the following drugs stimulates Alpha receptors causing mydriasis?
A. Acetylcholine
B. Physostigmine
C. Phenylephrine
D. Isoproterenol
E. Guanethidine

Answer: C. Phenylephrine

20. Following drug has weak action of dilation of coronary vessels as compared with others?
A. Nifedipine 
B. Verapamil 
C. Diltiazam
D. A & C
E. A & B

Answer: B. Verapamil 

21. One of the Following drugs is used to treat Genital (HSV) herpes simplex virus infection?

A. Valacyclovir

B. Cidofovir

C. Ganciclovir

D. Zanamivir

E. Lamivudine

Answer: A. Valacyclovir 

Famcyclovir, Pencyclovir, Acyclovir all are indicated for HSV. Cidofovir and Gancyclovir are indicated for Cyclomegalo virus retinitis. Zanamavir is used to treat influenza.

10. Labetalol blocks following receptors?
A. Alpha-1
B. Beta-1
C. Beta-2
D. A & B
C. All of the above 


Answer: All of the above

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PHARMACOLOGY QUIZZES 36 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug belongs to penicillins?
A. Niacin
B. Atorvastatin
C. Fenofibrate
D. Ezitimibe
E. Nafcillin 

Answer: E. Nafcillin

02. Which one of the following drugs is a Cephalosporin drug?
A. Niacin
B. Ceftibuten
C. Ampicillin 
D. Ezetimibe
E. Oxacillin

Answer: B. Ceftibuten


03. A drug that belongs to MONOBACTAMS is one of the following?
A. Ticarcillin 
B. Aztreonam
C. Cefazolin 
D. Sulbactam
E. Doripenem

Answer: B. Aztreonam

04. Which of the following drugs is used for hepatic viral infections?
A. Ibandronate
B. Oseltamivir  
C. Capecitabine
D. Interferon  
E. Naftifine

Answer: D. Interferon

05. Cefprozil belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: D. Antibiotics

06. Interferon  belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: A. Antiviral 

07. Benznidazole belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti malaria 

Answer: C. Antiprotozoal  


08. Melarsoprol belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antifungal  
E. Anti malaria 

Answer: C. Antiprotozoal

09. Indicate the antiseizure drug, which is a sulfonamide derivative, blocking Na+ channels and having additional ability to inhibit T-type Ca2+ channels?
a) Tiagabine
b) Zonisamide
c) Ethosuximide
d) Primidone

Answer: b) Zonisamide

10. Dawn phenomenon sometimes called dawn effect is linked with one of the following disease?
A. Diabeties mellitus
B. Achalasia
C. Hypertension
D. GERD 

Answer: A. Diabeties mellitus

11. Slow acting schizontocidal are all except:

a. pyrimethamine
b. proguanil
c. Sulfadoxine
d. ArtemisiniN

Answer: d. Artemisinin

13. An indication that ovulation has taken place is:
a) Increase in FSH levels
b) A drop in body temperature
c) Increase in serum LH
d) Increase in serum progesterone levels
e) Increase in serum estrogen levels


Answer: d). Increase in serum progesterone levels
the answer is d, progesterone production by the corpus luteum increases tremendously AT THE TIME of ovulation.  Both FSH and LH blood levels increase during the follicular phase of the menstrual cycle and reach peak levels JUST PRIOR TO OVULATION (not at the time of ovulation) The physiological SIGNAL for ovulation is a surge in LH levels.  Estrogen levels also increase but do not reach the levels reached during the follicular phase Progesterone affects the set point for thermoregulation and increases body temperature by approximately 0.5 F.

15. Which one of the following drugs is used to promote the ejection of breast milk?
A. Vasopressin
B. Oxytocin
C. Desmopressin
D. Phenytoin


Answer: B. Oxytocin

16. A decrease in HR (while stroke volume and peripheral resistance remain constant will cause increase in):
a) Arterial diastolic pressure
b) Arterial systolic pressure
c) Cardiac output
d) Arterial pulse pressure
e) Mean arterial pressure


Answer: d) Arterial pulse pressure
The answer is d, 
A decrease in heart rate causes increase in the diastole. This means that there is more time available for the arteries to empty. So the diastolic presseure will decrease and thus increase the pulse pressure (remember pulse pressure = systolic BP-diastolic BP). There should be no change in the systolic pressure since the after load, which is TPR hasn't changed.

17. Nonsystemic antacids are following?
A. Magnesium substance
B. Aluminum substance
C. Sodium Bicarbonate
D. A & B 
E. ALL of the above

Answer: D. A & B 

18. What is the antidote of Metoprolol?
A. Isoniazid
B. Pyridostigmine
C. Pyridoxine
D. Glucagon 
E. A & B 

Answer: D. Glucagon

19. Which one of the following drugs is used to treat the person addicted to nicotine (Smoking)?
A. Phentolamine
B. Varenicline
C. Mecamylamine
D. Scopolamine
E. Physostigmine

Answer: B. Varenicline

20. A drug that causes the increased risk of bleeding by inhibiting the hepatic metabolism of Warfarin?

A. Furosemide 
B. Fluconazole 
C. Griseofulvin  
D. Cholestyramine  
E. Bosenten

Answer: B. Fluconazole

12. Which of the following drug dosing need to be adjusted during radiotherapy sessions in patients to avoid extreme radiation toxicity:
a. 6 mercaptopurine
b. Vincristine
c. Cyclophosphamide
d. Dactinomycin


Answer: d. Dactinomycin

14. When a person moves from a supine to a standing position, which one of the following compensatory changes occurs?
a) Decreased cardiac output
b) Decreased heart rate
c) Decreased total peripheral resistance (TPR)
d) Increased contractility
e) Increased PR intervals


Answer: d) Increased contractility
The answer is D. Two important points to be noted: 
1. Vasomotor Center: The vasomotor center, located bilaterally mainly in the reticular substance of the medulla and of the lower third of the pons, is responsible for the overall control of blood distribution and pressure throughout the body. This center transmits parasympathetic impulses through the vagus nerves to the heart and transmits sympathetic impulses through the cord and peripheral sympathetic nerves to all or almost all the blood vessels of the body.
2. Baroreceptor Reflex: The baroreceptor reflex is the body's rapid response system for dealing with changes in blood pressure. This reflex is initiated by stretch receptors, called either baroreceptors or pressoreceptors, which are located in the walls of several of the large systemic arteries. Signals are sent to the vasomotor center, which response accordingly. 
So, when a person moves from a supine to a standing position, blood pools in the legs, causing decreased venous return, decreased cardiac output, and thus decreased blood pressure. This decrease in BP is detected by the baroreceptors, and signals sent to the vasomotor center, which response by increasing sympathetic outflow and decreasing parasympathetic outflow. This will cause an increase in heart rate (thus decrease in PR interval), increase contractility, and an increase in TPR. Increased HR and contractility will increase CO and BP back to normal.

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PHARMACOLOGY QUIZZES 35 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug belongs to penicillins?
A. Niacin
B. Atorvastatin
C. Fenofibrate
D. Ezetimibe
E. Piperacillin 

Answer: E. Piperacillin

02. Which one of the following drugs is a Cephalosporin drug?
A. Niacin
B. Ceftizoxime
C. Ampicillin 
D. Ezetimibe
E. Oxacillin

Answer: B. Ceftizoxime


03. A drug that belongs to CARBAPENEMS is one of the following?
A. Niacin
B. Aztreonam
C. Cefazolin 
D. Sulbactam
E. Doripenem

Answer: E. Doripenem

04. Triamterene belongs to one of the following classes of diuretics?
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium sparing diuretics
D. Osmotic Diuretics

Answer: C. Potassium-sparing Diuretics

05. Following is the 4th generation cephalosporin drug?
A. Cefdinir
B. Cefaclor
C. Cefadroxil
D. Cefepime
E. Cephalexin

Answer: D. Cefepime

06. Mechanism of action of oral hypoglycemic drug Acarbose?
A. The decrease in glucose absorption
B. Decrease hepatic production of glucose
C. Stimulates insulin secretion
D. Increase glucose secretion
E. Increase insulin secretion

Answer: A. The decrease in glucose absorption

07. Which one of the following drugs belongs to ANTIMETABOLITES drugs for Cancer?
A. 5-Fluorouracil
B. Capreomycin
C. Lamivudine 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: A. 5-Fluorouracil

08. Which of the following drug is a part of drugs for subcutaneous and systemic mycoses?
A. Ibandronate
B.  Posaconazole
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Posaconazole

09. Which of the following drug is a part of drugs for subcutaneous and systemic mycoses?
A. Ibandronate
B.  Ketoconazole
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Ketoconazole

10. Amikacin belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: D. Antibiotics

13. A 35-year-old patient with a history of asthma presents with hemoptysis and worsening of asthma. Blood tests reveal eosinophilia. He is diagnosed with Churg-Strauss syndrome. Which one of the following drugs is most likely to have precipitated this diagnosis?
a) Cromolyn Sodium
b) Flunisolide
c) Salmeterol
d) Zileuton
e) Zafirlukast


Answer: e) Zafirlukast
The answer is e, zafirlukast, there has been an association between LTD4 antagonists and Churg Strauss syndrome;  or allergic granulomatous angiitis is a rare syndrome that affects small- to medium-sized arteries and veins. Wegener granulomatosis, Churg-Strauss syndrome, and the microscopic form of periarteritis (ie, microscopic polyangiitis) are three closely related vasculitic syndromes that affect medium- and small-sized vessels and are associated with antibodies to neutrophil cytoplasmic antigens (ANCAs)
Churg-Strauss syndrome-like syndrome develops as a rare complication in people with asthma who are steroid-dependent and who are treated with leukotriene receptor antagonists (eg, montelukast, zafirlukast) upon reduction in their oral steroid dose. The Churg-Strauss syndrome-like complication is reported in people whose withdrawal of oral steroids is also facilitated by inhaled steroids. This complication is probably related to steroid withdrawal, which unmasks underlying Churg-Strauss syndrome, rather than to the drugs themselves. However, in rare cases, this syndrome has developed when a leukotriene receptor antagonist has been substituted for inhaled steroids without a history of oral steroid withdrawal. Other leukotriene modifiers like zileuton have been less implicated.


14. The principal androgen responsible for the development of male genitalia is?
a) Androstenedione
b) Dihydrotestosterone
c) Testosterone
d) Androsterone


Answer: b) Dihydrotestosterone

15. Which one of the following drugs is a Selective inhibitor of cytokine production and function?
A. Cyclosporine
B. Azathioprine
C. Daclizumab
D. Prednisolone


Answer: A. Cyclosporine

16. Systems antacid agent is one of the following drugs?
A. Magnesium substance
B. Aluminum substance
C. Sodium Bicarbonate
D. A & B 
E. ALL of the above

Answer:  C. Sodium Bicarbonate

17. According to the black box warning by the use of Adalimumab (anti-TNF-alpha agent) following risk and adverse effects is monitored carefully?
A. Severe loss of bone density
B. High potassium levels
C. Toxic megacolon
D. Risk of pneumonia


Answer: D. Risk of Pneumonia

18. Which of the following antihypertensive drug causes severe hypertension in massive overdose?
A. Methyldopa
B. Clonidine
C. Bethanidine
D. Guanethidine
E. Reserpine


Answer: B. Clonidine

19. A drug used to reduce the secretion of pepsin and gastric acid and promote the formation of mucus in the stomach?

A. Allopurinol
B. Misoprostol
C. Sulindac
D. Probenecid


Answer: B. Misoprostol

20. A 55-year-old woman comes to you with complaints of urinary incontinence for the last few months. Which one of the following drugs will you most likely prescribe her? 
a) Atropine
b) Hyoscine
c) Ipratropium
d) Pirenzepine
e) Tolterodine

Answer: e) Tolterodine

11. Somogyi effect is considered as one of the following terms?
A. Fasting hyperglycemia
B. Rebound hyperglycemia
C. Slow hyperglycemia 
D. A & B 

Answer: B. Rebound hyperglycemia

12. Which one of the following drugs blocks the Interleukin-2 receptor?
A. Basiliximab
B. Sirolimus
C. Azathioprine
D. Cyclosporine


Answer: A. Basiliximab

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PHARMACOLOGY QUIZZES 34 | Multiple Choice Questions| Medical Exam Preparations

01. Which one of the following drugs is a beta-blocker drug?
A. Lisinopril
B. Propranolol
C. Furosemide
D. Verapamil

Answer: B. Propranolol


02. Which of the following drug is a Calcium Channel Blocker?
A. Captopril
B. Atenolol
C. Diltiazem
D. Furosemide

Answer: C. Diltiazem

03. Which of the following drug is a Diuretic drug?
A. Captopril
B. Atenolol
C. Diltiazem
D. Furosemide

Answer: C. D. Furosemide

04. Which one of the following drugs is a Potassium-sparing Diuretics drug?
A. Chlorthalidone
B. Bumetanide
C. Amiloride
D. Acetazolamide

Answer: C. Amiloride


05. Cholesterol absorption antihyperlipidemic drug in the following list?
A. Colestipol
B. Fenofibrate
C. Simvastatin
D. Ezitimibe
E. Gemfibrozil

Answer: D. Ezetimibe


06. Bile acid sequestrant antihyperlipidemic drug in the following list?
A. Colesevelam
B. Fenofibrate
C. Simvastatin
D. Ezetimibe
E. Gemfibrozil

Answer: A. Colesevelam

07.  Glipizide belongs to which of the following diabetic agents?
A. Sulfonylureas
B. Meglitinide analogs
C. Biguanides Glitazones
D. Alpha glucosidase inhibitor
E. Thiazolidinediones

Answer: A. Sulfonylureas (ADRs: Weight gain, hypoglycaemia)

08. Which one of the following drugs belongs to ANTIMETABOLITES drugs for Cancer?
A. Gemcitabine
B. Capreomycin
C. Lamivudine 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: A. Gemcitabine 

09. Which of the following drugs is used for respiratory virus infections?
A. Ibandronate
B.  Amantadine
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Amantadine 

10. Which one of the following drugs belongs to ANTIMETABOLITES drugs for Cancer?
A. 6-Mercaptopurine
B. Capreomycin
C. Lamivudine 
D. Ezetimibe
E. Indanyl carbenicillin 

Answer: A. 6-Mercaptopurine 

11. Which of the following drugs is neuraminidase inhibitor drug?
A. Ibandronate
B.  Oseltamivir 
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Oseltamivir 

12. A drug that has a positive inotropic effect on the myocardium because it stimulates 𝛃1 receptor?
A. Dobutamine  
B. Clonidine 
C. Phenylephrine
D. Terbutaline 
E. Dipivefrin 

Answer: A. Dobutamine 

13. A drug that inhibits cytokine-stimulated cell proliferation is following?
A. Azathioprine
B. Cyclosporine
C. Basiliximab
D. Sirolimus


Answer: D. Sirolimus

14. "Pericarditis–myocarditis syndrome" is caused by which of the following cytotoxic agent??
A. Cisplatin
B. Busulfan
C. Streptozotocin
D. Vinblastine
E. Doxorubicin
F. Tamoxifen


Answer: E. Doxorubicin


15. Which one of the following agents will increase pulse pressure?
a) Adrenaline
b) Dopamine
c) Isoprenaline
d) Phenylephrine
e) Salbutamol


Answer: a) Adrenaline
The answer is A, Epinephrine has a positive ionotropic and chronotropic effect on the heart because of its beta 1-adrenergic activity. It also has an alpha-1 adrenergic activity that causes vasoconstriction in the vascular beds. These actions result in a rise in systolic blood pressure. Epinephrine also has beta 2-adrenergic activity, which causes vasodilation in skeletal muscle. Because of this latter effect, total peripheral resistance can fall, resulting in a drop in diastolic pressure, particularly at low doses of epinephrine. Pulse pressure = systolic BP – diastolic BP, so Epinephrine increases pulse pressure caused by the widening gap between systolic and diastolic BP.
Katzung has mentioned that Isoprenaline also decreases pulse pressure due to its beta 1 and beta 2 actions, however among the two adrenaline is slightly more likely to increase pulse pressure because it can further increase systolic BP via its alpha-1 agonist effect.

16. St. John’s wort may induce CYP3A4 isoenzymes and decrease cyclosporine to subtherapeutic levels. Type of interaction?
A. Drug-Drug
B. Drug-Chemical 
C. Drug-Food 
D. Drug-Herbal 
E. Drug-Laboratory 

Answer: D. Drug-Herbal 

17. Which one of the following receptor types is linked with Pupillary Dilation of smooth muscle cells in the eyes?
A. Alpha-1
B. Beta-1
C. Beta-2
D. M³ receptor
E. M¹ receptor

Answer: Alpha-1

18. The synaptic vesicle of an adrenergic neuron contains all of the following except?
A. Dopamine
B. Norepinephrine
C. Adenosine Triphosphate
D. Catechol-O-methyltransferase
E. Beta-hydroxylase

Answer: D. Catechol-O-methyltransferase

19. Which one of the following statements about the use of Celecoxib is incorrect?
A. Don't increase bleeding time 
B. Increase myocardial infarction 
C. More GI irritation than aspirin 
D. Used for osteoarthritis 
E. Reversible inhibitor 

Answer: C. More GI irritation than aspirin

20. A patient comes to the emergency ward with recent organophosphorus compound poisoning.The symptom not shown in this patient would be:

a) Bronchodilatation
b) Diarrhea
c) Increased lacrimation
d) Increased salivation
e) Muscle Weakness


Answer: a) Bronchodilatation

21. Exaggerated IgE mediated response causes Atopic diseases e.g asthma rhinitis, are what type of hypersensitivity?

A. Type I

B. Type II

C. Type III

D. Type IV

Answer: A. Type I

Hypersensitivity: exaggerated immune response that is harmful to the individual.

Type I hypersensitivity: also known as immediate hypersensitivity or allergy and include atopy e.g allergic rhinitis or hay fever, food allergies, eczema, Asthma and anaphylaxis.

Caused by elevated IgE production, IgE being bound by Fc epsilon receptor on the surface of mast cells this IgE bound to mast cells causes release of others mediators e.g histamine.

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PHARMACOLOGY QUIZZES 33 | Multiple Choice Questions| Medical Exam Preparations

01. Which of the following drug belongs to penicillins?
A. Niacin
B. Atorvastatin
C. Fenofibrate
D. Ezetimibe
E. Penicillin G 

Answer: E. penicillin G

02. Which one of the following drugs is a Cephalosporin drug?
A. Niacin
B. Ceftazidime
C. Ampicillin 
D. Ezetimibe
E. Oxacillin

Answer: B. Ceftazidibe


03. A drug that belongs to Beta-lactamase inhibitors is one of the following?
A. Niacin
B. Aztreonam
C. Cefazolin 
D. Sulbactam
E. Imipenem

Answer: D. Sulbactam

04. Eplerenone belongs to one of the following classes of diuretics?
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium sparing diuretics
D. Carbonic anhydrase inhibitors

Answer: C. Potassium-sparing Diuretics

05. Spironolactone belongs to one of the following classes of diuretics?
A. Thiazide Diuretic
B. Loop Diuretics
C. Potassium sparing diuretics
D. Osmotic Diuretics

Answer: C. Potassium-sparing Diuretics

06. Which one of the following drugs belongs to the alkylating agent?
A. Gemcitabine
B. Capreomycin
C. Lamivudine 
D. Busulfan
E. Indanyl carbenicillin 

Answer: D. Busulfan 

07. Which of the following drugs is used for respiratory virus infections?
A. Ibandronate
B. Ribavirin
C. Capecitabine
D. Miconazole
E. Naftifine

Answer: B. Ribavirin 

08. Ceftibuten belongs to the class of following drugs?
A. Antiviral 
B. Antipyretic 
C. Antiprotozoal
D. Antibiotics 
E. Anti-malaria 

Answer: D. Antibiotics

09. Increase in peripheral resistance causes one of the following issues?
A. High Blood pressure 
B. Fever 
C. Aids
D. Headache 

Answer: A. High Blood pressure

11. Patients with this type of Seizure started staring and exhibiting eye blinking Which lasts for 3 to 5 seconds?
A. Status epilepticus 
B. Myoclonic seizure
C. Absence Seizure
D. Tonic-clonic Seizure
E. Simple seizure

Answer: C. Absence Seizure

12. Which of the following corticosteroid had a salt retaining effect? 
A. Prednisone
B. Dexamethasone
C. Fludrocortisone
D. Ethamethasoneb
E. Cortisone

Answer: C. Fludrocortisone

13. Which one of the following drugs is used to slow down premature labor when administered systemically?
A. Epinephrine 
B. Clonidine 
C. Phenylephrine
D. Terbutaline 
E. Dipivefrin 

Answer: D. Terbutaline 
Terbutaline is used to slow down premature labor by relaxing uterus muscles that are responsible for expelling the fetus at the time of premature labor.

14. A drug that inhibits purine synthesis is one of the following?
A. Azathioprine
B. Sirolimus
C. Tacrolimus
D. Basiliximab


Answer: A. Azathioprine


15. The maximum daily dose of Acetaminophen for no longer than 10 days for pain is following?
A. 660 mg
B. 1200 mg
C. 2000 mg
D. 4000 mg
E. 6000 mg

Answer: D. 4000 mg

16. Which one of the following would occur as a result of the inhibition of Na/K/ATPase?
a) Decreased intracellular Na concentration
b) Increased intracellular K concentration
c) Increased intracellular Ca concentration
d) Increased Na-glucose cotransport
e) Increased Na-Ca exchange


Answer: c) Increased intracity Ca concentration
The answer is C, inhibition of Na/K ATPase leads to an increase in intracellular Na concentration, increased intracellular Na then leads to decreased Na gradient across the cell membrane, thereby inhibiting the Ca/Na exchange and causing an increase in intracellular Ca concentration. This is the basis of the major mechanism of action of cardiac glycosides like Digoxin.

17. The rate of conduction of action potentials along a nerve will be increased by:
a) Stimulating the Na-K Pump
b) Inhibiting the Na-K Pump
c) Decreasing the diameter of the nerve
d) Myelinating the nerve
e) Lengthening the nerve fiber


Answer: d) Myelinating the nerve
The answer is D, myelin insulates the nerve thus increasing conduction velocity; action potentials can only be generated at the nodes of Ranvier, where there are breaks in the insulation. The activity of the Na/K pump does not directly affect the conduction or formation of action potentials. Decreasing nerve diameter would increase internal resistance and therefore slow down conduction velocity.

18. A patient diagnosed with type 2 diabetes is administered an oral dose of 0.1 mg chlorpropamide, an insulin secretagogue, and weak acid with a pKa of 5.0. What is the quantity of chlorpropamide absorbed at ph 2.0 from the stomach?
A. 01 mg
B. 05 mg
C. 50 μg
D. 90 μg
E. 9 μg

Answer: E. 9 μg

19. Which one of the following drugs is indicated in hepatic edema & cirrhosis as diuretic of choice?
A. Furosemide
B. Chlorthalidone
C. Acetazolamide
D. Spironolactone


Answer: D. Spironolactone

20. Which one of the following statements about the use of Insulin is Wrong?
A. Stimulates hepatic glycogen synthesis
B. Increase protein synthesis
C. Inhibit peripheral uptake of Glucose
D. Inhibit lipolysis

Answer: C. Inhibit peripheral uptake of Glucose

10. Only one portion of the brain is involved in this type of Seizure?
A. Partial seizure
B. Generalized seizure
C. Febrile seizure
D. Absence seizure
E. Tonic-Clonic seizure

Answer: A. Partial seizure

21. Process in which phagocytosis is enhanced by the deposit of ------------- e.g antibody or compliment component C3b on the surface of antigen?

A. Opsonins, Opsonization

B. Paratope

C. Plasma Cells 

D. Selection tolerance 

E. Natural killer cell 

Answer: A. Opsonins, and process is called Opsonisation 

Paratope: Antigen binding Site also known as antibody combining site on an antibody. Consists of interaction between the Vh and Vl domains of the antibody.

22. Undifferentiated cells found in the bone marrow and fatal liver that gives rise to nearly every leukocyte(immune cell) found in the body?

A. Mitogen

B. MHC haplotype

C. Lysozyme 

D. Commensal

E. Hematopoietic stem cells 

Answer: E. Hematopoietic stem cells 

Mitogen: Molecule that causes cells to undergo cells division 

MHC haplotype: major histocompatibility complex MHC genes both class I and class II expressed by an individual.

Lysozyme: A family of enzymes that breakdown walls of bacteria, especially gram positive bacteria.

Commensal: Normal microbial flora of digestive tract and skin. A Commensal relationship bw a microorganism and it's host is  one which the microorganisms benefits and host neither is harmed nor benifits. 

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